CCR 5 deficiency/ CCR 5Δ32: resistant to HIV infection at the cost of curtailed CD 4 + T cell memory responses

Human memory CCR 4 1 CD 8 1 T cell subset has the ability to produce multiple cytokines

The CC chemokine receptor (CCR)4 is associated with trafficking of specialized cutaneous memory type 2 Th cells in the skin. However, a CD8 1 T cell population expressing CCR4 still remains uncharacterized. In the present study, we investigated the expression and function of CCR4 on human CD8 T cells and characterized CCR4CD8 human T cells. Multi-color flow cytometric analysis revealed that CCR...

ACHOUR et al . CD 4 - CCR 5 INTERACTION 1 CHEMOKINES , CYTOKINES , AND INTERLEUKINES CD 4 interacts with CCR 5 in intracellular compartments and contributes to receptor expression at the cell surface

The association of CD4, a glycoprotein involved in T cell development and antigen recognition, and CCR5, a chemotactic G protein-coupled receptor, which regulates trafficking and effector functions of immune cells, forms the main receptor for the human immunodeficiency virus HIV. We observed that the vast majority of CCR5 is maintained within the intracellular compartments of primary T lymphocy...

Functional CCR 7 + CD 4 In Vivo Differentiated Cytokine - Producing

Expression of Integrin Type 1 Infection Regardless of Their Preferential Targets for Productive HIV T Cells Are + CD 4 + Memory CCR

Mutant chemokine receptor (CCR-5) and its relevance to HIV infection in Arabs.

(st4529, st4547, st4532, st4545, and st3018, with accession numbers AF060368, AF052426, AF077666, AF077668, and AF077669, respectively). The newly found group A st4545 sequence was more similar to various group G streptococcal emm sequences than to known group A emm sequences. One group G isolate had a previously found group G 5' emm sequence (stLG6, accession number U25741). The nongroupable S...